About

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche. We are seeking a Software Engineer with extensive GPU programming experience and a passion for bioinformatics and advanced algorithm development to create GPU-accelerated tools for DNA sequencing data analysis. In this role, you will design and implement high-performance computational algorithms—leveraging both traditional bioinformatics methods and deep learning models—optimized for the throughput and accuracy requirements of next-generation sequencing technologies. You will work closely with a multidisciplinary team of scientists and engineers to transform sequencing data into actionable biological insights. The Opportunity: Develop and optimize GPU-accelerated algorithms for real-time analysis of sequencing data, including basecalling, alignment, variant detection, and other genomic data processing tasks. Collaborate with bioinformaticians and molecular biologists to translate computational challenges in genomics into robust, scalable software solutions. Implement and optimize neural network and other machine learning algorithms on GPU, adapting them for large-scale, high-throughput sequencing data. Contribute to the design and implementation of novel sequence analysis algorithms, including signal processing, error correction, and statistical modeling. Author dependable, readable, maintainable, and well-structured code in C++ and CUDA, following best practices for scientific and production software. Work with the data scientists to accelerate existing algorithms or pipelines. Stay current with advances in computational genomics, GPU computing, and algorithmic techniques; proactively research and integrate new methods as appropriate. Who you are: Bachelor's degree in Computer Science, Computer Engineering, or a related field, with 5+ years of relevant experience (MS/PhD is advantageous). Expertise in bioinformatics algorithm development, with a focus on sequence analysis, variant calling, or genomic workflows. Proficient in object-oriented programming (C++) and GPU programming using CUDA, including familiarity with GPU-accelerated libraries like cuDNN or Thrust. Advanced experience in systems programming for parallel Linux applications involving both CPUs and GPUs, with strong debugging and optimization skills. Solid grasp of machine learning and deep learning, particularly in relation to biological data, along with experience using frameworks like PyTorch, TensorFlow, or JAX. Skilled in Python for prototyping, analysis, and integrating bioinformatics pipelines, as well as interfacing deep learning models with custom algorithms. Excellent analytical, problem-solving, and communication skills, with a proven ability to deliver innovative scientific solutions and work effectively in cross-disciplinary teams. Relocation benefits are not available for this posting. Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an Equal Opportunity Employer. We believe it’s urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives. We are courageous in both decision and action. And we believe that good business means a better world. That is why we come to work each day. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow. We are proud of who we are, what we do, and how we do it. We are many, working as one across functions, across companies, and across the world. We are Roche.