
Jr. Research Laboratory Technologist
Hamilton Health Sciences
2 hours ago
•No application
About
- The Junior Research Laboratory Technologist in the Jeschke Burn Research Laboratory will support cutting-edge research in burn immunology, metabolism, and regenerative medicine. Working under the supervision of the Laboratory Director, this role involves conducting experimental studies, assisting with complex in-vitro and in-vivo procedures, and ensuring that laboratory processes meet the highest scientific and regulatory standards. The technologist will contribute directly to the lab’s mission of advancing knowledge and developing innovative therapies for burn patients.
Key Responsibilities Include
- · Conduct experimental research in burn immunology, metabolism, and regenerative medicine.
- · Perform animal surgeries and post-operative care in compliance with ethical standards and approved animal protocols.
- · Manage, operate, and maintain specialized laboratory instruments, including the Seahorse XF Analyzer, Flow Cytometer, and Cytation C10.
- · Prepare, process, and analyze biological samples such as tissues, blood, and cell cultures.
- · Perform advanced assays, including flow cytometry, metabolic flux analysis, high-resolution imaging, and organoid culture.
- · Maintain accurate laboratory records, protocols, and databases to ensure traceability and reproducibility of research findings.
- · Train and mentor graduate students, postdoctoral fellows, and research staff in laboratory methods and procedures.
- · Ensure compliance with institutional, provincial, and federal regulations related to biosafety, animal use, and ethical research practices.
- · Collaborate with internal and external partners on research projects, funding proposals, and grant applications.
- · Contribute to manuscript preparation, conference presentations, and progress reports, supporting the dissemination of research findings.
- · Coordinate laboratory organization, including bench assignments, equipment scheduling, and safety checks.
- · Actively participate in lab meetings and scientific discussions to advance shared research goals.
- · Lead the design, execution, and refinement of in-vivo preclinical models to support translational surgical research , including survival and non-survival procedures, peri-procedural monitoring, and longitudinal outcome assessment.
- · Develop and maintain procedural SOPs and ensure studies are conducted under approved compliance regulation with
- complete source documentation and audit-ready records.
- · Translate clinical questions into rigorous preclinical experiments, integrating protocol development, REDCap database build/maintenance, and SPSS-based analysis for high-quality, reproducible data.
- · Serve as a technical trainer for junior staff/trainees in basic surgical skills and study procedures, drawing on prior
- experience in a surgical skills lab environment. · Perform survival surgical procedures and related peri-operative care; collect and process biospecimens per protocol.
- · Contribute to grant preparation and manuscript figures/tables grounded in validated preclinical datasets.
- · Education: Master of Science (MSc) or higher in biomedical sciences, immunology, physiology, or a related field.
- Advanced training in laboratory research or animal science is considered an asset. Medical/surgical training with hands-on animal model experience including laparotomy and vascular cut-downs, with documented compliance to institutional animal care protocols.
- · Experience: Minimum 2 years of hands-on laboratory research experience, preferably in immunology, metabolism, regenerative medicine, or a related biomedical field. Experience with animal research models and compliance with ethical protocols is strongly preferred.
- · Technical Skills: Proficiency in animal surgeries, specimen collection, and post-operative care.
- · Experience with specialized instruments such as the Seahorse XF Analyzer, Flow Cytometer, and Cytation C10.
- · Skilled in advanced assays, including flow cytometry, metabolic flux analysis, imaging, and organoid culture.
- · Strong foundation in cell culture, tissue processing, and blood sample preparation.
- · Regulatory & Safety Knowledge: Working knowledge of biosafety regulations, animal care protocols, and ethical research
- compliance at the institutional, provincial, and federal levels. Completion of Transportation of Dangerous Goods (TDG) training is an asset.
- · Data & Documentation: Ability to maintain accurate laboratory records, prepare standard operating procedures, and manage research databases. Proficiency with MS Office, GraphPad Prism, and other data analysis software.
- · Collaboration & Leadership: Strong interpersonal skills to train and mentor graduate students, postdoctoral fellows, and technical staff, as well as to collaborate effectively with internal and external research partners.
- · Communication: Excellent written and oral communication skills for contributing to grant applications, manuscripts, conference presentations, and progress reports.
- · Organizational Skills: Ability to coordinate lab operations, equipment scheduling, bench assignments, and safety checks while managing multiple projects simultaneously.
- · Scientific Mindset: Demonstrated critical thinking, problem-solving abilities, and active participation in scientific discussions and lab meetings to advance shared research goals
Assets
- · Prior experience working in a biomedical research laboratory.
- · Knowledge of metabolism and immunology, particularly as applied to burn or regenerative medicine research.
- · Familiarity with porcine models for translational and preclinical research.
- · Experience working in a surgical skills/innovation laboratory environment, delivering hands-on instruction in basic surgical techniques and safety.
- · Specialized blend of clinical surgical training and in-vivo preclinical model execution